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Illiams Wilkins Co., Baltimore, Md. 122. Hori, H., and S. Osawa. 1987. Origin and evolution of Organisms as deduced from 5S ribosomal RNA sequences. Mol. Biol. Evol. 4:445?72. 123. Horner, D. S., R. P. Hirt, S. Kilvington, D. Lloyd, and T. M. Embley. 1996. Molecular data suggest an early acquisition of the mitochondrion endosymbiont. Proc. R. Soc. London Ser. B 263:1053?059. 124. Inouye, M. 1979
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Get your company to arouse the interest of the Chinese investors with IPO Pang’s experts who assist the financial investment seekers in China with contacts.
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Ds Enzymol. 266:418?27. 62. Felsenstein, J. 1997. Cases in which parsimony and compatibility methods will be positively misleading. Syst. Zool. 27:401?10. 63. Feng, D. F., G. Cho, and R. F. Doolittle. 1997. Determining divergence times with a protein clock: update and reevaluation. Proc. Natl. Acad. Sci. USA 94:13028?3033. 64. Fitch, W. M. 1997. Toward defining the course of evolution: minimum cha
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Their sequences. Curr. Opin. Genet. Dev. 7:764?70. 70. Forterre, P., N. Benachenhou-Lahfa, F. Confalonieri, M. Duguet, C. Elie, and B. Labedan. 1992. The nature of the last universal ancestor and the root of the tree of life, still open questions. Biosystems 28:15?2. 71. Fox, G. E., E. Stackebrandt, R. B. Hespell, J. Gibson, J. Maniloff, T. A. Dyer, R. S. Wolfe, W. E. Balch, R. S. Tanner, L. J. Ma
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Uctal carcinoma in situ (DCIS) component or infiltrating lobular carcinoma compared with infiltrating ductal carcinomas (both P
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Inter-quartile after normalization on the reference gene set. cP for Spearman rank correlation test. dP for Mann-Whitney U test. eP for Kruskal-Wallis test, including a Wilcoxon-type test for trend when appropriate. fWith quantitative polymerase chain reaction cut point for positive versus negative ESR1 and PGR, 0.2 and 0.1, respectively, and for ESR2 at the median level of 0.005 (mRNA levels rela
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Urse of the disease without the confounding effect of systemic adjuvant therapy), we restricted our next analyses of MFS to those 837 LNN disease patients who had not received (neo)adjuvant systemic therapy. The significant relationships of DC-SCRIPT as a continuous variable in these univariate analyses justified the use of the previously identified cut point that dichotomized the cohort in 33.3
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Urse of the disease without the confounding effect of systemic adjuvant therapy), we restricted our next analyses of MFS to those 837 LNN disease patients who had not received (neo)adjuvant systemic therapy. The significant relationships of DC-SCRIPT as a continuous variable in these univariate analyses justified the use of the previously identified cut point that dichotomized the cohort in 33.3
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Homologs: implications regarding origin of eukaryotic cells and of endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 91:2895?899. 103. Gupta, R. S., K. Bustard, M. Falah, and D. Singh. 1997. Sequencing of heat shock protein 70 (DnaK) homologs from Deinococcus proteolyticus and Thermomicrobium roseum and their integration in a protein-based phylogeny of prokaryotes. J. Bacteriol. 179:345?57. 104. G
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Mith, T. 1987. Eukaryotes with no mitochondria. Nature 326: 332?33. 30. Cavalier-Smith, T. 1987. The origin of eukaryotic and archaebacterial cells. Ann. N. Y. Acad. Sci. 503:17?4. 30a.Cavalier-Smith, T. 1991. The evolution of cells, p. 271?04. In S. Osawa and T. Honjo (ed.), Evolution of life. Springer-Verlag, Tokyo, Japan. 31. Cavalier-Smith, T. 1992. Origins of secondary metabolism. Ciba Found.
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Inter-quartile after normalization on the reference gene set. cP for Spearman rank correlation test. dP for Mann-Whitney U test. eP for Kruskal-Wallis test, including a Wilcoxon-type test for trend when appropriate. fWith quantitative polymerase chain reaction cut point for positive versus negative ESR1 and PGR, 0.2 and 0.1, respectively, and for ESR2 at the median level of 0.005 (mRNA levels rela
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Of a part of the type 1 LacNAc (Gal -1,3-GlcNAc) and type 2 LacNAc (Gal -1,4-GlcNAc) structures that build the scaffold for blood group H and Lewis-type units (58). Some human pathogens use the GlcNAc residue as a binding receptor; e.g., the fimbrial adhesin F17-G of enterotoxigenic E. coli binds to N-acetylglucosamine-presenting receptors on the microvilli of the intestinal epithelium of ruminant
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Ltivariable analyses, increasing levels of DC-SCRIPT were associated with good prognosis only for pT1 (small tumor without lymphatic/vascular invasion) tumors and not for larger tumors. These and additional exploratory Cox univariate analyses are summarized in Table 3. The prognostic value of DC-SCRIPT is visualized in KaplanMeier curves (Figure 1) as a dichotomized variable in these biologically
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Rotein TCP-1 and the `chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins. Biochem. Int. 20:833?41. 96. Gupta, R. S. 1995. Evolution of the chaperonin families (Hsp60, Hsp10 and Tcp-1) of proteins and the origin of eukaryotic cells. Mol. Microbiol. 15: 1?1. 97. Gupta, R. S. 1995. Phylogenetic analysis of the 90 kD heat shock family of protein sequences and
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Nts whose relapse was treated with first-line tamoxifen monotherapy. These patients had not received (neo) adjuvant endocrine systemic treatment. In univariate analyses, no statistically significant associations were observed between DC-SCRIPT as transformed continuous variable and PFS or clinical benefit after start of first-line treatment with tamoxifen (HR = 1.08 [0.99 to 1.18], P = 0.07 and od
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Ic immunoprecipitation and input DNA. H3K9, Lysine 9 of histone H3; H4K8, Lysine 8 of histone H4; H3K4, Lysine 4 of histone H3; H4K20, Lysine 20 of histone H4; ac, acetylated; me, monomethylated; me2, dimethylated; me3, trimethylated. The significant p-values are shown.Schwarzenbach et al. BMC Cancer 2014, 14:796 http://www.biomedcentral.com/1471-2407/14/Page 10 ofTherefore, the predominant occurr
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On of MAGE-A1 expressionIn order to functionally investigate the impact of BORIS on promoter settings, we examined the influence of BORIS on the activity of the methylated MAGE-A1 promoter in the context of transcription factors Ets-1 and Sp1. We transiently co-transfected methylated reporter plasmids pGL2/MAGE-A1 (-77/+183) containing the BORIS binding site located downstream of the start site (F
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Complex. We show for the first time, that Sp1 also interacted with BORIS and MBD1v1, which up- and downregulate MAGE-A1 promoter activity, respectively, but this protein-protein interaction was much weaker than its interaction with Ets-1 and hTBP amino-terminus. Conversely, hTBP interacted with MBD2b, BORIS, Ets-1 and Sp1 (Figure 7A). For the interaction with MBD2b and BORIS the evolutionarily con
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Rotein TCP-1 and the `chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins. Biochem. Int. 20:833?41. 96. Gupta, R. S. 1995. Evolution of the chaperonin families (Hsp60, Hsp10 and Tcp-1) of proteins and the origin of eukaryotic cells. Mol. Microbiol. 15: 1?1. 97. Gupta, R. S. 1995. Phylogenetic analysis of the 90 kD heat shock family of protein sequences and
1
Rotein TCP-1 and the `chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins. Biochem. Int. 20:833?41. 96. Gupta, R. S. 1995. Evolution of the chaperonin families (Hsp60, Hsp10 and Tcp-1) of proteins and the origin of eukaryotic cells. Mol. Microbiol. 15: 1?1. 97. Gupta, R. S. 1995. Phylogenetic analysis of the 90 kD heat shock family of protein sequences and
1
Of a part of the type 1 LacNAc (Gal -1,3-GlcNAc) and type 2 LacNAc (Gal -1,4-GlcNAc) structures that build the scaffold for blood group H and Lewis-type units (58). Some human pathogens use the GlcNAc residue as a binding receptor; e.g., the fimbrial adhesin F17-G of enterotoxigenic E. coli binds to N-acetylglucosamine-presenting receptors on the microvilli of the intestinal epithelium of ruminant
1
On of MAGE-A1 expressionIn order to functionally investigate the impact of BORIS on promoter settings, we examined the influence of BORIS on the activity of the methylated MAGE-A1 promoter in the context of transcription factors Ets-1 and Sp1. We transiently co-transfected methylated reporter plasmids pGL2/MAGE-A1 (-77/+183) containing the BORIS binding site located downstream of the start site (F
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D S. G. Oliver. 1996. Life with 6000 genes. Science 274:546, 563?67. 81. Gogarten, J. P., H. Kibak, P. Dittrich, L. Taiz, E. J. Bowman, B. J. Bowman, M. F. Manolson, R. J. Poole, T. Date, and T. Oshima. 1989. Evolution of the vacuolar H -ATPase: implications for the origin of eukaryotes. Proc. Natl. Acad. Sci. USA 86:6661?665. 82. Gogarten, J. P., T. Starke, H. Kibak, J. Fishman, and L. Taiz. 1992
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Uctal carcinoma in situ (DCIS) component or infiltrating lobular carcinoma compared with infiltrating ductal carcinomas (both P
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